This article is a broad review on the strategies to cure the rare genetic disorders which are incurable conditions affecting the development and livelihood of the diseased. Before we start with the strategies, let us first know what are the rare genetic disorders? Rare Genetic Disorders These disorders are caused by the mutation i.e. sudden change in a gene sequence that results in the production of faulty protein or complete absence of the protein. If there is a problem in a

With the advent of the Yamanaka factors, it became possible to regenerate the damaged cells or tissue in adults which was impossible previously. This research area is fascinating for the numerous possibilities of regeneration it holds. Let’s have a broad view on this technology having vast scope in the future. What are iPSCs? “iPSCs” stand for induced pluripotent stem cells. First of all, stem cells are the cells in our body having the ability to repair, renew and regenerati

The discovery of CRISPR-Cas9 opened doors to explore the area of genomics in a new way. It shows the numerous possibilities to unlock the genome and lock it again through it’s highly specific and accurate nature. It’s major application in medical field as a therapeutic option for rare genetic disorders fascinated me a lot and thus, it became my area of research interest. Let’s deep dive into the fascinating world of CRISPR-Cas9 and explore the possibilities it holds. Discove

Lived Experience, Rights, and Responsibility I am a person with disability (PwD) diagnosed with Muscular Dystrophy , a rare neuromuscular genetic disorder classified under locomotor disability as per the Rights of Persons with Disabilities (RPwD) Act, 2016 . Muscular dystrophy is a progressive condition caused by the absence or dysfunction of essential muscle proteins, leading to muscle weakness and functional limitations. Living with a genetic condition from early childhoo